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A previous search, using the Connectivity Map developed by the Broad Institute, found that GHK could alleviate impairment of TGFβ1 signaling (Pickart et al., 2017), a pathway associated with Aβ deposition and neurofibrillary tangle formation (Bosco et al., 2013)

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Oxygen free radicals mediate the induction of manganese superoxide dismutase gene expression by TNF-α in human oral carcinoma SCC-25 cells